Statistical Mechanics of Pluripotency
نویسندگان
چکیده
Recent reports using single-cell profiling have indicated a remarkably dynamic view of pluripotent stem cell identity. Here, we argue that the pluripotent state is not well defined at the single-cell level but rather is a statistical property of stem cell populations, amenable to analysis using the tools of statistical mechanics and information theory.
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ورودعنوان ژورنال:
- Cell
دوره 154 شماره
صفحات -
تاریخ انتشار 2013